Histamine downregulates CD14 expression via H2 receptors on human monocytes

Histamine downregulates CD14 expression via H2 receptors on human monocytes

Lipopolysaccharide (LPS) binds to LPS-binding protein (LBP) in plasma and is delivered to the cell surface receptor CD14 on human monocyte. LPS is transferred to the transmembrane signaling receptor toll-like receptor (TLR) 4. In the present study, the effect of histamine on the expression of CD14 o...

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Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 108(2003), 3 vom: 19. Sept., Seite 274-81
1. Verfasser: Takahashi, Hideo Kohka (VerfasserIn)
Weitere Verfasser: Morichika, Toshihiko, Iwagaki, Hiromi, Tamura, Ryuji, Kubo, Shinichiro, Yoshino, Tadashi, Mori, Shuji, Akagi, Tadaatsu, Tanaka, Noriaki, Nishibori, Masahiro
Format: Aufsatz
Sprache:English
Veröffentlicht: 2003
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Histamine Agonists Histamine H2 Antagonists Lipopolysaccharide Receptors Lipopolysaccharides Methylhistamines Receptors, Histamine H2 Tumor Necrosis Factor-alpha 4-methylhistamine mehr... 54ST71P9EE Histamine 820484N8I3 Dimaprit ZZQ699148P