C5a causes limited, polymorphonuclear cell-independent, mesenteric ischemia/reperfusion-induced injury

C5a causes limited, polymorphonuclear cell-independent, mesenteric ischemia/reperfusion-induced injury

C5 is critical in the development of local mucosal damage and inflammation as well as in the development of remote organ injury after mesenteric ischemia/reperfusion (IR). To define the role of C5a in tissue injury, we treated wild-type mice with a cyclic hexapeptide C5a receptor antagonist (C5aRa)...

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Publié dans:Clinical immunology (Orlando, Fla.). - 1999. - 108(2003), 3 vom: 19. Sept., Seite 263-73
Auteur principal: Fleming, Sherry D (Auteur)
Autres auteurs: Mastellos, Dimitrios, Karpel-Massler, Georg, Shea-Donohue, Terez, Lambris, John D, Tsokos, George C
Format: Article
Langue:English
Publié: 2003
Accès à la collection:Clinical immunology (Orlando, Fla.)
Sujets:Comparative Study Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S. Antigens, CD Complement C5 Complement Membrane Attack Complex Eicosanoids Receptor, Anaphylatoxin C5a Receptors, Complement plus... Recombinant Proteins Vascular Cell Adhesion Molecule-1 Integrin alpha4 143198-26-9 Complement C5a 80295-54-1