C5a causes limited, polymorphonuclear cell-independent, mesenteric ischemia/reperfusion-induced injury

C5a causes limited, polymorphonuclear cell-independent, mesenteric ischemia/reperfusion-induced injury

C5 is critical in the development of local mucosal damage and inflammation as well as in the development of remote organ injury after mesenteric ischemia/reperfusion (IR). To define the role of C5a in tissue injury, we treated wild-type mice with a cyclic hexapeptide C5a receptor antagonist (C5aRa)...

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Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 108(2003), 3 vom: 19. Sept., Seite 263-73
1. Verfasser: Fleming, Sherry D (VerfasserIn)
Weitere Verfasser: Mastellos, Dimitrios, Karpel-Massler, Georg, Shea-Donohue, Terez, Lambris, John D, Tsokos, George C
Format: Aufsatz
Sprache:English
Veröffentlicht: 2003
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Comparative Study Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S. Antigens, CD Complement C5 Complement Membrane Attack Complex Eicosanoids Receptor, Anaphylatoxin C5a Receptors, Complement mehr... Recombinant Proteins Vascular Cell Adhesion Molecule-1 Integrin alpha4 143198-26-9 Complement C5a 80295-54-1