Humoral, mucosal, and cellular immune responses to oral Norwalk virus-like particles in volunteers

Humoral, mucosal, and cellular immune responses to oral Norwalk virus-like particles in volunteers

Norwalk virus-like particles (VLPs), made from recombinant capsid protein, are a promising vaccine. Thirty-six healthy adult volunteers received 250 microg (n = 10), 500 microg (n = 10), or 2000 microg (n = 10) of orally administered VLP or placebo (n = 6). All vaccinees developed significant rises...

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Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 108(2003), 3 vom: 19. Sept., Seite 241-7
1. Verfasser: Tacket, Carol O (VerfasserIn)
Weitere Verfasser: Sztein, Marcelo B, Losonsky, Genevieve A, Wasserman, Steven S, Estes, Mary K
Format: Aufsatz
Sprache:English
Veröffentlicht: 2003
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Clinical Trial Journal Article Research Support, U.S. Gov't, P.H.S. Antibodies, Viral Immunoglobulin A, Secretory Immunoglobulin G Vaccines, Synthetic Viral Vaccines Interferon-gamma 82115-62-6