Improving selection of alphaIIbbeta3-binding phage antibodies with increased reactivity derived from immunized donors

Improving selection of alphaIIbbeta3-binding phage antibodies with increased reactivity derived from immunized donors

Although many studies of the immune response in polytransfused Glanzmann thrombasthenia (GT) patients and in autoimmune thrombocytopenic purpura (AITP) have demonstrated the frequent development of Abs directed against the alphaIIbbeta3 integrin, little is known about the induced anti-alphaIIbbeta3...

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Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 108(2003), 3 vom: 19. Sept., Seite 199-210
1. Verfasser: Jacobin, M J (VerfasserIn)
Weitere Verfasser: Robert, R, Pouns, O, Laroche-Traineau, J, Nurden, A, Peter, K, Little, M, Clofent-Sanchez, G
Format: Aufsatz
Sprache:English
Veröffentlicht: 2003
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Case Reports Journal Article Research Support, Non-U.S. Gov't Antibodies, Monoclonal Autoantibodies Complementarity Determining Regions Immunoglobulin Heavy Chains Immunoglobulin Light Chains Oligopeptides Peptide Library mehr... Platelet Glycoprotein GPIIb-IIIa Complex arginyl-glycyl-aspartic acid 78VO7F77PN