Ajulemic acid, a nonpsychoactive cannabinoid acid, induces apoptosis in human T lymphocytes

Ajulemic acid, a nonpsychoactive cannabinoid acid, induces apoptosis in human T lymphocytes

Oral administration of ajulemic acid (AjA), a synthetic nonpsychoactive cannabinoid acid, prevents joint cartilage and bone damage in an experimental model of arthritis in rats. Joint tissue injury in patients with rheumatoid arthritis (RA) is due in part to activation of T lymphocytes in the synovi...

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Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 108(2003), 2 vom: 15. Aug., Seite 95-102
1. Verfasser: Bidinger, Bonnie (VerfasserIn)
Weitere Verfasser: Torres, Roxabella, Rossetti, Ronald G, Brown, Lisa, Beltre, Rosa, Burstein, Sumner, Lian, Jane B, Stein, Gary S, Zurier, Robert B
Format: Aufsatz
Sprache:English
Veröffentlicht: 2003
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. Annexin A5 Antirheumatic Agents Dronabinol 7J8897W37S CASP3 protein, human EC 3.4.22.- Caspase 3 mehr... Caspases Fluorescein-5-isothiocyanate I223NX31W9 lenabasum OGN7X90BT8