Generation of protective immunity by inactivated recombinant staphylococcal enterotoxin B vaccine in nonhuman primates and identification of correlates of immunity

Generation of protective immunity by inactivated recombinant staphylococcal enterotoxin B vaccine in nonhuman primates and identification of correlates of immunity

At this time there are no vaccines or therapeutics to protect against staphylococcal enterotoxin B (SEB) exposure. Here, we report vaccine efficacy of an attenuated SEB in a nonhuman primate model following lethal aerosol challenge and identify several biomarkers of protective immunity. Initial in v...

Ausführliche Beschreibung

Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 108(2003), 1 vom: 15. Juli, Seite 51-9
1. Verfasser: Boles, James W (VerfasserIn)
Weitere Verfasser: Pitt, M Louise M, LeClaire, Ross D, Gibbs, Paul H, Torres, Edna, Dyas, Beverly, Ulrich, Robert G, Bavari, Sina
Format: Aufsatz
Sprache:English
Veröffentlicht: 2003
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Cytokines Enterotoxins Histocompatibility Antigens Class II Vaccines, Inactivated Vaccines, Synthetic enterotoxin B, staphylococcal 39424-53-8