The Delta 32 mutation of the chemokine-receptor 5 gene neither is correlated with chronic hepatitis C nor does it predict response to therapy with interferon-alpha and ribavirin

The Delta 32 mutation of the chemokine-receptor 5 gene neither is correlated with chronic hepatitis C nor does it predict response to therapy with interferon-alpha and ribavirin

Unlike in HIV, homozygosity for a 32-bp deletion (Delta 32) of the chemokine receptor 5 (CCR5) gene was recently described in increased frequency in patients with chronic hepatitis C (HCV). Thus, it was speculated that this mutation might be relevant for disease susceptibility and influence the resp...

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Détails bibliographiques
Publié dans:Clinical immunology (Orlando, Fla.). - 1999. - 108(2003), 1 vom: 15. Juli, Seite 46-50
Auteur principal: Glas, J (Auteur)
Autres auteurs: Török, H P, Simperl, C, König, A, Martin, K, Schmidt, F, Schaefer, M, Schiemann, U, Folwaczny, C
Format: Article
Langue:English
Publié: 2003
Accès à la collection:Clinical immunology (Orlando, Fla.)
Sujets:Journal Article Antiviral Agents Interferon-alpha Receptors, CCR5 Ribavirin 49717AWG6K