Clinical study of plasma substitute (Gelofusion) on fluid resuscitation in patients with burned shock

OBJECTIVE: To investigate the effects of plasma substitute(Gelofusion) on fluid resuscitation in patients with burned shock

Bibliographische Detailangaben
Veröffentlicht in:Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue. - 1998. - 15(2003), 5 vom: 01. Mai, Seite 265-7
1. Verfasser: Zhao, Xiao-dong (VerfasserIn)
Weitere Verfasser: Dang, Wei, He, Zhong-jie, Zhang, Xian, Yan, Bai-gang, Yao, Yong-ming
Format: Aufsatz
Sprache:Chinese
Veröffentlicht: 2003
Zugriff auf das übergeordnete Werk:Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue
Schlagworte:English Abstract Journal Article Randomized Controlled Trial Research Support, Non-U.S. Gov't Succinates succinylated gelatin 39340-57-3 Gelatin 9000-70-8
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100 1 |a Zhao, Xiao-dong  |e verfasserin  |4 aut 
245 1 0 |a Clinical study of plasma substitute (Gelofusion) on fluid resuscitation in patients with burned shock 
264 1 |c 2003 
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500 |a Date Completed 22.10.2012 
500 |a Date Revised 02.07.2003 
500 |a published: Print 
500 |a Citation Status MEDLINE 
520 |a OBJECTIVE: To investigate the effects of plasma substitute(Gelofusion) on fluid resuscitation in patients with burned shock 
520 |a METHODS: Twenty burn shock patients with total body surface area (TBSA) more than 40% were enrolled for clinical study on the effect of resuscitation with plasma substitute (Gelofusion). The patients were randomly divided into two groups: Gelofusion resuscitation group (n=11) and plasma resuscitation group (n=9). The cardiac output (CO),oxygen delivery (DO2), packed cell volume (PCV), blood and plasma viscosity, lactate(LA) and base deficit (BD) levels were detected at shock stage (postburn from 1 to 48 hours) 
520 |a RESULTS: Two hours after rapid fluid replacement, the levels of CO and DO2 were gradually increased, while the levels of PCV, blood and plasma viscosity, LA and BD were markedly decreased (P<0.05 or P<0.01). After resuscitation, plasma viscosity in Gelofusion resuscitation group were obviously lower than that in plasma resuscitation group within 24 hours postburn (all P<0.05).With an exception of plasma viscosity, there were no significant differences in other parameters between two groups at various intervals (all P>0.05) 
520 |a CONCLUSION: In the resuscitation of burn shock, the clinical effect of Gelofusion treatment is similar to that of plasma treatment. Gelofusion appears to be a fairly good plasma substitute for extensive application on the management of burn shock during the early stage 
650 4 |a English Abstract 
650 4 |a Journal Article 
650 4 |a Randomized Controlled Trial 
650 4 |a Research Support, Non-U.S. Gov't 
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650 7 |a succinylated gelatin  |2 NLM 
650 7 |a 39340-57-3  |2 NLM 
650 7 |a Gelatin  |2 NLM 
650 7 |a 9000-70-8  |2 NLM 
700 1 |a Dang, Wei  |e verfasserin  |4 aut 
700 1 |a He, Zhong-jie  |e verfasserin  |4 aut 
700 1 |a Zhang, Xian  |e verfasserin  |4 aut 
700 1 |a Yan, Bai-gang  |e verfasserin  |4 aut 
700 1 |a Yao, Yong-ming  |e verfasserin  |4 aut 
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773 1 8 |g volume:15  |g year:2003  |g number:5  |g day:01  |g month:05  |g pages:265-7 
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