Reconstitution of B cell function in murine models of immunodeficiency

Murine models of immunodeficiency were used to evaluate strategies that might allow B cell engraftment in patients with X-linked agammaglobulinemia. Mice with defects in Btk or mu heavy chain were given 2.5 x 10(6) bone marrow cells from wild-type congenic donors. In the absence of any preparative r...

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Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 107(2003), 2 vom: 30. Mai, Seite 90-7
1. Verfasser: Porpiglia, Andrea S (VerfasserIn)
Weitere Verfasser: Rohrer, Jurg, Conley, Mary Ellen
Format: Aufsatz
Sprache:English
Veröffentlicht: 2003
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. Immunoglobulin G Immunoglobulin M Immunoglobulin mu-Chains Ficoll 25702-74-3 DNA 9007-49-2 mehr... Protein-Tyrosine Kinases EC 2.7.10.1 Agammaglobulinaemia Tyrosine Kinase EC 2.7.10.2