Immune responses in breast cancer patients immunized with an anti-idiotype antibody mimicking NeuGc-containing gangliosides

A phase I clinical trial was conducted in patients with stage III/IV breast cancer who were treated with the anti-idiotype mAb 1E10 specific to an Ab1 mAb able to react specifically with N-glycolyl-containing gangliosides and with antigens expressed on human melanoma and breast carcinoma cells. Pati...

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Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 107(2003), 2 vom: 30. Mai, Seite 80-9
1. Verfasser: Díaz, Alain (VerfasserIn)
Weitere Verfasser: Alfonso, Mauro, Alonso, Ruby, Saurez, Giselle, Troche, Mayelín, Catalá, Mauricio, Díaz, Rosa María, Pérez, Rolando, Vázquez, Ana María
Format: Aufsatz
Sprache:English
Veröffentlicht: 2003
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Clinical Trial Clinical Trial, Phase I Journal Article Research Support, Non-U.S. Gov't Antibodies, Anti-Idiotypic Antibodies, Monoclonal Antibodies, Neoplasm Cancer Vaccines G(M3) Ganglioside