Tissue stiffness imaging method using temporal variation of ultrasound speckle pattern

Applying vibration to a medium makes it vibrate. The resulting change in scatterer distribution inside the medium due to applied vibration changes the speckle pattern of ultrasound images. In this case, scatterers in a hard medium experience small displacements, and those in a soft medium experience...

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Veröffentlicht in:IEEE transactions on ultrasonics, ferroelectrics, and frequency control. - 1999. - 50(2003), 4 vom: 21. Apr., Seite 457-60
1. Verfasser: Jeong, Mok-Kun (VerfasserIn)
Weitere Verfasser: Kwon, Sung-Jae
Format: Aufsatz
Sprache:English
Veröffentlicht: 2003
Zugriff auf das übergeordnete Werk:IEEE transactions on ultrasonics, ferroelectrics, and frequency control
Schlagworte:Letter Research Support, Non-U.S. Gov't
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520 |a Applying vibration to a medium makes it vibrate. The resulting change in scatterer distribution inside the medium due to applied vibration changes the speckle pattern of ultrasound images. In this case, scatterers in a hard medium experience small displacements, and those in a soft medium experience large displacements. As a result, the amount of speckle pattern brightness change in ultrasound images is related to the tissue stiffness. Using this dependency, a two-dimensional profile of relative tissue stiffness can be constructed qualitatively at the display pixel resolution by determining at each pixel the standard deviation and/or the difference between minimum and maximum values over a certain number of consecutive B-mode images. Experiments with phantoms show that the softer the tissue, the larger the standard deviation. The proposed imaging modality is a simple yet practical method of resolving hard cysts surrounded by soft background in a phantom using B-mode frame data only 
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