The calcium-binding protein S100A12 induces neutrophil adhesion, migration, and release from bone marrow in mouse at concentrations similar to those found in human inflammatory arthritis

The calcium-binding protein S100A12 induces neutrophil adhesion, migration, and release from bone marrow in mouse at concentrations similar to those found in human inflammatory arthritis

We investigated the proinflammatory activities of S100A12 in the context of synovial inflammation. S100A12 levels were increased in the synovial fluids and plasma of patients with gout, rheumatoid arthritis, psoriatic arthritis, and undetectable in osteoarthritis, a noninflammatory disorder. S100A12...

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Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 107(2003), 1 vom: 01. Apr., Seite 46-54
1. Verfasser: Rouleau, Pascal (VerfasserIn)
Weitere Verfasser: Vandal, Karen, Ryckman, Carle, Poubelle, Patrice E, Boivin, Annie, Talbot, Mariève, Tessier, Philippe A
Format: Aufsatz
Sprache:English
Veröffentlicht: 2003
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Calcium-Binding Proteins Chemokine CCL4 Macrophage Inflammatory Proteins S100 Proteins S100A12 Protein S100A12 protein, human