Environmental polycyclic aromatic hydrocarbons, benzo(a) pyrene (BaP) and BaP-quinones, enhance IgE-mediated histamine release and IL-4 production in human basophils

Environmental polycyclic aromatic hydrocarbons, benzo(a) pyrene (BaP) and BaP-quinones, enhance IgE-mediated histamine release and IL-4 production in human basophils

Polycyclic aromatic hydrocarbons (PAHs) are major components of diesel exhaust particles found in pollutant respirable particles. There is growing evidence that these fossil fuel combustion products exacerbate allergic inflammation. Basophils contribute to allergic inflammation through the release o...

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Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 107(2003), 1 vom: 01. Apr., Seite 10-9
1. Verfasser: Kepley, Christopher L (VerfasserIn)
Weitere Verfasser: Lauer, Fredine T, Oliver, Janet M, Burchiel, Scott W
Format: Aufsatz
Sprache:English
Veröffentlicht: 2003
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. Air Pollutants Oxidants Quinones Reactive Oxygen Species Receptors, IgE Vehicle Emissions Interleukin-4 mehr... 207137-56-2 Benzo(a)pyrene 3417WMA06D Immunoglobulin E 37341-29-0 Acetylcysteine WYQ7N0BPYC