In vitro evidence that subcutaneous administration of glatiramer acetate induces hyporesponsive T cells in patients with multiple sclerosis

Glatiramer acetate (GA; Copaxone) is a random sequence polypeptide used in the treatment of relapsing remitting multiple sclerosis (RR MS). We have recently demonstrated that prior to treatment, GA induces proliferation of resting T cells and is not cross-reactive with myelin antigens. Daily GA inje...

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Veröffentlicht in:	Clinical immunology (Orlando, Fla.). - 1999. - 106(2003), 3 vom: 01. März, Seite 163-74
1. Verfasser:	Schmied, M (VerfasserIn)
Weitere Verfasser:	Duda, P W, Krieger, J I, Trollmo, C, Hafler, D A
Format:	Aufsatz
Sprache:	English
Veröffentlicht:	2003
Zugriff auf das übergeordnete Werk:	Clinical immunology (Orlando, Fla.)
Schlagworte:	Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. Cytokines Interleukin-2 Peptides Recombinant Proteins Glatiramer Acetate 5M691HL4BO