Characterization of antibody responses to endogenous and exogenous antigen in the nonobese diabetic mouse
It is suggested that a T-helper cell 2 (Th2) shift and Th2 spreading of autoimmunity following immunization with beta-cell antigen causes diabetes protection. To address this, antibody titer and subclass to insulin, glutamic acid decarboxylase (GAD)65, IA-2, and IA-2beta proteins were measured by ra...
| Publié dans: | Clinical immunology (Orlando, Fla.). - 1999. - 106(2003), 2 vom: 01. Feb., Seite 155-62 |
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| Auteur principal: | |
| Autres auteurs: | , , , , |
| Format: | Article |
| Langue: | English |
| Publié: |
2003
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| Accès à la collection: | Clinical immunology (Orlando, Fla.) |
| Sujets: | Comparative Study Journal Article Research Support, Non-U.S. Gov't Adjuvants, Immunologic Autoantibodies Autoantigens Diphtheria-Tetanus-Pertussis Vaccine ICA512 autoantibody Immunoglobulin G Insulin plus... |