Anti-GM-CSF titer predicts response to GM-CSF therapy in pulmonary alveolar proteinosis

Anti-GM-CSF titer predicts response to GM-CSF therapy in pulmonary alveolar proteinosis

Pulmonary alveolar proteinosis (PAP) is an idiopathic disease characterized by the accumulation of surfactant in the pulmonary airspaces. The development of a PAP-like syndrome in the GM-CSF knockout mouse and resolution of disease by local GM-CSF expression strongly implicates GM-CSF in surfactant...

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Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 105(2002), 3 vom: 17. Dez., Seite 342-50
1. Verfasser: Bonfield, Tracey L (VerfasserIn)
Weitere Verfasser: Kavuru, Mani S, Thomassen, Mary Jane
Format: Aufsatz
Sprache:English
Veröffentlicht: 2002
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, U.S. Gov't, P.H.S. Antibodies Granulocyte-Macrophage Colony-Stimulating Factor 83869-56-1