Proatherogenic and proinflammatory properties of immune complexes prepared with purified human oxLDL antibodies and human oxLDL

Proatherogenic and proinflammatory properties of immune complexes prepared with purified human oxLDL antibodies and human oxLDL

Immune complexes (IC) prepared with human low density lipoprotein (LDL) and rabbit LDL antibodies induce foam cell transformation of human macrophages and activate the release of proinflammatory mediators by human macrophages and THP-1 cells. Because the affinity of human oxidized LDL (oxLDL) antibo...

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Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 105(2002), 1 vom: 30. Okt., Seite 81-92
1. Verfasser: Virella, G (VerfasserIn)
Weitere Verfasser: Atchley, D, Koskinen, Sinikka, Zheng, D, Lopes-Virella, Maria F, DCCT/EDIC Research Group
Format: Aufsatz
Sprache:English
Veröffentlicht: 2002
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S. Antigen-Antibody Complex Immunoglobulin Isotypes Lipoproteins, LDL Tumor Necrosis Factor-alpha oxidized low density lipoprotein Cholesterol 97C5T2UQ7J