In vivo activation of myelin oligodendrocyte glycoprotein-specific T cells in healthy control subjects

Autoreactive T cells are present in healthy subjects but are assumed not to induce overt disease due to lack of exposure to autoantigen or because of immune regulation. In EAE, activation of myelin protein-specific T cells is a crucial step in disease induction. In this study, we evaluated whether m...

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Publié dans:Clinical immunology (Orlando, Fla.). - 1999. - 105(2002), 2 vom: 01. Nov., Seite 185-91
Auteur principal: Burns, James B (Auteur)
Autres auteurs: Bartholomew, Breck D, Lobo, Stephen T
Format: Article
Langue:English
Publié: 2002
Accès à la collection:Clinical immunology (Orlando, Fla.)
Sujets:Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S. Autoantigens MOG protein, human Myelin Proteins Myelin-Associated Glycoprotein Myelin-Oligodendrocyte Glycoprotein Leukocyte Common Antigens EC 3.1.3.48