Fluorescence-based functional assay for Wnt/beta-catenin signaling activity

Fluorescence-based functional assay for Wnt/beta-catenin signaling activity

Aberrant activation of beta-catenin signaling has been implicated in the development of human cancers. As a Wnt signal transducer, beta-catenin forms a complex with the lymphocyte enhancer-binding factor/T cell factor transcription factor and activates downstream targets that promote cell proliferat...

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Bibliographische Detailangaben
Veröffentlicht in:BioTechniques. - 1991. - 33(2002), 5 vom: 21. Nov., Seite 1126-8, 1130, 1132 passim
1. Verfasser: Zhou, L (VerfasserIn)
Weitere Verfasser: An, N, Jiang, W, Haydon, R, Cheng, H, Zhou, Q, Breyer, B, Feng, T, He, T-C
Format: Aufsatz
Sprache:English
Veröffentlicht: 2002
Zugriff auf das übergeordnete Werk:BioTechniques
Schlagworte:Research Support, Non-U.S. Gov't Technical Report Journal Article CTNNB1 protein, human CTNNB1 protein, mouse Culture Media, Conditioned Cytoskeletal Proteins DNA-Binding Proteins GAL4 protein, S cerevisiae Luminescent Proteins mehr... Neoplasm Proteins Proto-Oncogene Proteins Recombinant Fusion Proteins Saccharomyces cerevisiae Proteins Trans-Activators Transcription Factors WNT1 protein, human Wnt Proteins Wnt1 Protein Wnt1 protein, mouse Zebrafish Proteins beta Catenin Green Fluorescent Proteins 147336-22-9 Luciferases EC 1.13.12.-