Successful salvage chemotherapy with gemcitabine, etoposide and cisplatin for metastatic ureteral cancer : a case report
A 35-year-old man who had undergone nephroureterectomy and a single cycle of adjuvant MVAC chemotherapy for the left ureteral cancer was referred our clinic for the treatment of paraaortic lymph node metastases. Following histologic confirmation of transitional cell carcinoma by computed tomography...
| Veröffentlicht in: | Hinyokika kiyo. Acta urologica Japonica. - 1962. - 48(2002), 7 vom: 05. Juli, Seite 427-30 |
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| 1. Verfasser: | |
| Weitere Verfasser: | , , , |
| Format: | Aufsatz |
| Sprache: | Japanese |
| Veröffentlicht: |
2002
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| Zugriff auf das übergeordnete Werk: | Hinyokika kiyo. Acta urologica Japonica |
| Schlagworte: | Case Reports English Abstract Journal Article Deoxycytidine 0W860991D6 Etoposide 6PLQ3CP4P3 Cisplatin Q20Q21Q62J Gemcitabine |
| Zusammenfassung: | A 35-year-old man who had undergone nephroureterectomy and a single cycle of adjuvant MVAC chemotherapy for the left ureteral cancer was referred our clinic for the treatment of paraaortic lymph node metastases. Following histologic confirmation of transitional cell carcinoma by computed tomography (CT) guided biopsy, we treated him with combination chemotherapy consisting of ifosfamide, 5-fluorouracil, etoposide and cisplatin. After 5 cycles of chemotherapy complete remission was obtained. Six months later, however, metastases recurred in the left supraclavicular and paraaortic lymph nodes. Thus, we treated him with a new combination chemotherapy comprising gemcitabine, etoposide and cisplatin which was approved as a phase I study by the institutional review board. Although he was the first patient enrolled in the study and received the minimum dose of gemcitabine (level 1), complete remission was again achieved. Adjuvant radiotherapy of 40 Gy was given to the metastatic sites. He has been well without evidence of disease for 12 months |
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| Beschreibung: | Date Completed 05.11.2002 Date Revised 07.12.2022 published: Print Citation Status MEDLINE |
| ISSN: | 0018-1994 |