Aberrant T-cell antigen receptor-mediated responses in autoimmune lymphoproliferative syndrome

Aberrant T-cell antigen receptor-mediated responses in autoimmune lymphoproliferative syndrome

Autoimmune Lymphoproliferative Syndrome (ALPS) is a disorder of defective lymphocyte apoptosis due to mutations of the Fas receptor and other molecules in the Fas signaling pathway. In addition to accumulation of CD4(-) CD8(-) double-negative (DN) T cells, many patients display a dysregulated cytoki...

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Détails bibliographiques
Publié dans:Clinical immunology (Orlando, Fla.). - 1999. - 104(2002), 1 vom: 02. Juli, Seite 31-9
Auteur principal: Goldman, Frederick D (Auteur)
Autres auteurs: Vibhakar, Rajeev, Puck, Jennifer M, Straus, Stephen E, Ballas, Zuhair K, Hollenback, Clay, Loew, Thomas, Thompson, Anthony, Song, Kejing, Cook, Robert T
Format: Article
Langue:English
Publié: 2002
Accès à la collection:Clinical immunology (Orlando, Fla.)
Sujets:Case Reports Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. Antigens, CD Antigens, Differentiation, T-Lymphocyte CD69 antigen Interleukin-2 Lectins, C-Type Receptors, Antigen, T-Cell plus... Receptors, Interleukin-2 fas Receptor Interleukin-4 207137-56-2 Interferon-gamma 82115-62-6 Calcium SY7Q814VUP