The function of the chloroplast 2-cysteine peroxiredoxin in peroxide detoxification and its regulation

The Arabidopsis genome contains nine open reading frames with homology to members of the peroxiredoxin (prx) family: one 1-Cys-prx, two 2-Cys-prx, five type II-prx, and one peroxiredoxin Q. The function of the peroxiredoxins in plant metabolism is only slowly emerging. They are assumed to reduce tox...

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Veröffentlicht in:Journal of experimental botany. - 1985. - 53(2002), 372 vom: 23. Mai, Seite 1321-9
1. Verfasser: Dietz, K J (VerfasserIn)
Weitere Verfasser: Horling, F, König, J, Baier, M
Format: Aufsatz
Sprache:English
Veröffentlicht: 2002
Zugriff auf das übergeordnete Werk:Journal of experimental botany
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Review Antioxidants Peroxides Peroxidases EC 1.11.1.- Peroxiredoxins EC 1.11.1.15 Ascorbic Acid PQ6CK8PD0R
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100 1 |a Dietz, K J  |e verfasserin  |4 aut 
245 1 4 |a The function of the chloroplast 2-cysteine peroxiredoxin in peroxide detoxification and its regulation 
264 1 |c 2002 
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500 |a Date Revised 21.11.2013 
500 |a published: Print 
500 |a Citation Status MEDLINE 
520 |a The Arabidopsis genome contains nine open reading frames with homology to members of the peroxiredoxin (prx) family: one 1-Cys-prx, two 2-Cys-prx, five type II-prx, and one peroxiredoxin Q. The function of the peroxiredoxins in plant metabolism is only slowly emerging. They are assumed to reduce toxic peroxides to their corresponding alcohols with a rather broad substrate specificity. The 2-Cys peroxiredoxins (2-CP) were recently identified as members of the antioxidant defence system of chloroplasts. Knock-out mutants of Synechocystis and antisense mutants of Arabidopsis have provided insight into the function of 2-CPs in the photosynthetic antioxidant network. This review summarizes present knowledge on the enzymatic mechanism, the physiological context and the genetic regulation of the 2-CPs in plants and cyanobacteria. In addition, an extrapolation on the metabolic role of the chloroplast 2-CP is attempted based on the molecular features of 2-CPs from other organisms 
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650 4 |a Research Support, Non-U.S. Gov't 
650 4 |a Review 
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650 7 |a Peroxides  |2 NLM 
650 7 |a Peroxidases  |2 NLM 
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650 7 |a Peroxiredoxins  |2 NLM 
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700 1 |a Horling, F  |e verfasserin  |4 aut 
700 1 |a König, J  |e verfasserin  |4 aut 
700 1 |a Baier, M  |e verfasserin  |4 aut 
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