Spontaneous secretion of immunoglobulins and anti-HIV-1 antibodies by in vivo activated B lymphocytes from HIV-1-infected subjects monocyte and natural killer cell requirement for in vitro terminal differentiation into plasma cells

Spontaneous secretion of immunoglobulins and anti-HIV-1 antibodies by in vivo activated B lymphocytes from HIV-1-infected subjects : monocyte and natural killer cell requirement for in vitro terminal differentiation into plasma cells

Peripheral blood mononuclear cells from HIV-1-infected subjects secrete spontaneously in vitro immunoglobulins (Ig) and anti-HIV-1 antibodies (Ab). Purified B lymphocytes secrete only minute amounts of Ig and anti-HIV-1 Ab compared with unfractionated cells. Monocytes and natural killer cells enhanc...

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Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 103(2002), 1 vom: 30. Apr., Seite 98-109
1. Verfasser: Fournier, Anne Marie (VerfasserIn)
Weitere Verfasser: Fondere, Jean-Michel, Alix-Panabieres, Catherine, Merle, Corinne, Baillat, Vincent, Huguet, Marie-France, Taïb, Jacques, Ohayon, Viviane, Zembala, Marek, Reynes, Jacques, Vendrell, Jean Pierre
Format: Aufsatz
Sprache:English
Veröffentlicht: 2002
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Antigens, CD Antigens, Differentiation, B-Lymphocyte CD40 Antigens CD71 antigen Cell Adhesion Molecules HIV Antibodies Immunoglobulins Interleukin-6 Receptors, Transferrin