Role of RANTES in the development of autoimmune tissue injuries in MRL-Fas lpr mice

Role of RANTES in the development of autoimmune tissue injuries in MRL-Fas lpr mice

MRL-Fas lpr mice spontaneously develop a severe autoimmune disease closely resembling human SLE. To investigate the possible role of RANTES in autoimmune tissue injuries, we have constructed RANTES-deficient MRL-Fas lpr mice by gene targeting. In the RANTES-deficient mice, axillary lymph nodes were...

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Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 103(2002), 1 vom: 30. Apr., Seite 89-97
1. Verfasser: Tsukahara, Tsunemichi (VerfasserIn)
Weitere Verfasser: Makino, Yasuhiko, Fujii, Takayuki, Ogawa, Makoto, Saisho, Hiromitsu, Hamano, Yuki, Ueda, Shiro, Akikusa, Bunshiro, Danoff, Theodore M
Format: Aufsatz
Sprache:English
Veröffentlicht: 2002
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Autoantibodies Chemokine CCL5 DNA 9007-49-2