A complement-dependent model of thrombotic thrombocytopenic purpura induced by antibodies reactive with endothelial cells

A complement-dependent model of thrombotic thrombocytopenic purpura induced by antibodies reactive with endothelial cells

Thrombotic thrombocytopenic purpura (TTP) is an immunologically mediated disease characterized by thrombocytopenia, hemolytic anemia, and pathologic changes in various organs, including the kidney, which are secondary to widespread thromboses. Central to TTP is platelet activation, which may occur f...

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Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 103(2002), 1 vom: 30. Apr., Seite 43-53
1. Verfasser: Ren, Guohui (VerfasserIn)
Weitere Verfasser: Hack, Bradley K, Minto, Andrew W, Cunningham, Patrick N, Alexander, Jessy J, Haas, Mark, Quigg, Richard J
Format: Aufsatz
Sprache:English
Veröffentlicht: 2002
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. Antibodies, Monoclonal Immunoglobulin G Complement System Proteins 9007-36-7