Ab initio prediction of helical segments in polypeptides

An ab initio method has been developed to predict helix formation for polypeptides. The approach relies on the systematic analysis of overlapping oligopeptides to determine the helical propensity for individual residues. Detailed atomistic level modeling, including entropic contributions, and solvat...

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Détails bibliographiques
Publié dans:Journal of computational chemistry. - 1984. - 23(2002), 2 vom: 30. Jan., Seite 245-66
Auteur principal: Klepeis, J L (Auteur)
Autres auteurs: Floudas, C A
Format: Article
Langue:English
Publié: 2002
Accès à la collection:Journal of computational chemistry
Sujets:Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S. DNA-Binding Proteins G-substrate Nerve Tissue Proteins Peptides Plant Proteins Repressor Proteins Viral Proteins plus... Viral Regulatory and Accessory Proteins Wheat Germ Agglutinins chymotrypsin inhibitor 2 phage repressor proteins Aprotinin 9087-70-1