Evolution of physics-based methodology for exploring the conformational energy landscape of proteins

Evolution of physics-based methodology for exploring the conformational energy landscape of proteins

The evolution of our physics-based computational methods for determining protein conformation without the introduction of secondary-structure predictions, homology modeling, threading, or fragment coupling is described. Initial use of a hard-sphere potential captured much of the structural propertie...

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Bibliographische Detailangaben
Veröffentlicht in:Journal of computational chemistry. - 1984. - 23(2002), 1 vom: 15. Jan., Seite 28-34
1. Verfasser: Scheraga, Harold A (VerfasserIn)
Weitere Verfasser: Pillardy, Jaroslaw, Liwo, Adam, Lee, Jooyoung, Czaplewski, Cezary, Ripoll, Daniel R, Wedemeyer, William J, Arnautova, Yelena A
Format: Aufsatz
Sprache:English
Veröffentlicht: 2002
Zugriff auf das übergeordnete Werk:Journal of computational chemistry
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S. Proteins