Computational alanine scanning of the 1:1 human growth hormone-receptor complex
The MM-PBSA (Molecular Mechanics-Poisson-Boltzmann surface area) method was applied to the human Growth Hormone (hGH) complexed with its receptor to assess both the validity and the limitations of the computational alanine scanning approach. A 400-ps dynamical trajectory of the fully solvated comple...
| Veröffentlicht in: | Journal of computational chemistry. - 1984. - 23(2002), 1 vom: 15. Jan., Seite 15-27 |
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| 1. Verfasser: | |
| Weitere Verfasser: | , |
| Format: | Aufsatz |
| Sprache: | English |
| Veröffentlicht: |
2002
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| Zugriff auf das übergeordnete Werk: | Journal of computational chemistry |
| Schlagworte: | Journal Article Research Support, U.S. Gov't, P.H.S. Receptors, Somatotropin Growth Hormone 9002-72-6 Alanine OF5P57N2ZX |