Attenuated production of intracellular IL-10 and IL-12 in monocytes from patients with severe asthma

Attenuated production of intracellular IL-10 and IL-12 in monocytes from patients with severe asthma

Interleukin (IL)-10 and IL-12 production is decreased in peripheral blood mononuclear cells of patients with mild asthma. Using whole blood culture and flow cytometry we examined whether monocyte heterogeneity influenced IL-10 and IL-12 production in subjects with severe asthma. We demonstrated that...

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Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 102(2002), 3 vom: 22. März, Seite 258-66
1. Verfasser: Tomita, Katsuyuki (VerfasserIn)
Weitere Verfasser: Lim, Sam, Hanazawa, Toyoyuki, Usmani, Omar, Stirling, Rob, Chung, K Fan, Barnes, Peter J, Adcock, Ian M
Format: Aufsatz
Sprache:English
Veröffentlicht: 2002
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Lipopolysaccharide Receptors Receptors, IgG Interleukin-10 130068-27-8 Interleukin-12 187348-17-0