Millennium award recipient contribution. Identification of children with early onset and high incidence of anti-islet autoantibodies

Millennium award recipient contribution. Identification of children with early onset and high incidence of anti-islet autoantibodies

A total of 21,000 general population newborns (NECs) and 693 young siblings-offspring of patients with type 1A diabetes (SOCs) were class II genotyped and 293 NECs and 72 SOCs with the high-risk genotype, DR3/4, DQB1*0302 have been prospectively evaluated. Seventeen individuals who converted to pers...

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Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 102(2002), 3 vom: 22. März, Seite 217-24
1. Verfasser: Robles, David T (VerfasserIn)
Weitere Verfasser: Eisenbarth, George S, Wang, Tianbao, Erlich, Henry A, Bugawan, Teodorica L, Babu, Sunanda R, Barriga, Kathy, Norris, Jill M, Hoffman, Michelle, Klingensmith, Georgeanna, Yu, Liping, Rewers, Marian, Diabetes Autoimmunity Study in the Young
Format: Aufsatz
Sprache:English
Veröffentlicht: 2002
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. Autoantibodies HLA-A Antigens HLA-DQ Antigens HLA-DQ beta-Chains HLA-DQB1 antigen HLA-DR3 Antigen HLA-DR4 Antigen mehr... Histocompatibility Antigens Class I Histocompatibility Antigens Class II Insulin