Radiobiological studies with the nematode Caenorhabditis elegans. Genetic and developmental effects of high LET radiation
The biological effects of heavy charged particle (HZE) radiation are of particular interest to travellers and planners for long-duration space flights where exposure levels represent a potential health hazard. The unique feature of HZE radiation is the structured pattern of its energy deposition in...
| Veröffentlicht in: | International Journal Of Radiation Applications And Instrumentation. Part D, Nuclear Tracks And Radiation Measurements. - 1990. - 20(1992), 1 vom: 07. Jan., Seite 227-32 |
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| Format: | Aufsatz |
| Sprache: | English |
| Veröffentlicht: |
1992
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| Zugriff auf das übergeordnete Werk: | International Journal Of Radiation Applications And Instrumentation. Part D, Nuclear Tracks And Radiation Measurements |
| Schlagworte: | Comparative Study Journal Article Research Support, U.S. Gov't, Non-P.H.S. NASA Center JPL NASA Discipline Number 00-00 NASA Discipline Number 04-10 NASA Discipline Radiation Health NASA Experiment Number 284050 1/1 NASA Program Flight NASA Program Radiation Health mehr... |
| Zusammenfassung: | The biological effects of heavy charged particle (HZE) radiation are of particular interest to travellers and planners for long-duration space flights where exposure levels represent a potential health hazard. The unique feature of HZE radiation is the structured pattern of its energy deposition in targets. There are many consequences of this feature to biological endpoints when compared with effects of ionizing photons. Dose vs response and dose-rate kinetics may be modified, DNA and cellular repair systems may be altered in their abilities to cope with damage, and the qualitative features of damage may be unique for different ions. The nematode Caenorhabditis elegans is being used to address these and related questions associated with exposure to radiation. HZE-induced mutation, chromosome aberration, cell inactivation and altered organogenesis are discussed along with plans for radiobiological experiments in space |
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| Beschreibung: | Date Completed 10.05.1995 Date Revised 05.11.2019 published: Print Citation Status MEDLINE |
| ISSN: | 0735-245X |