A case of renal cell carcinoma producing alpha-fetoprotein
Renal cell carcinoma (RCC) producing alpha-fetoprotein (AFP) is a rare condition with only 11 cases reported in Japan to our knowledge. A 69-year-old man was admitted to our hospital for further examination of an incidental right renal tumor. Laboratory tests showed markedly increased serum level of...
| Publié dans: | Hinyokika kiyo. Acta urologica Japonica. - 1962. - 47(2001), 7 vom: 05. Juli, Seite 477-80 |
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| Auteur principal: | |
| Autres auteurs: | , , , , , , , |
| Format: | Article |
| Langue: | Japanese |
| Publié: |
2001
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| Accès à la collection: | Hinyokika kiyo. Acta urologica Japonica |
| Sujets: | Case Reports English Abstract Journal Article Review alpha-Fetoproteins |
| Résumé: | Renal cell carcinoma (RCC) producing alpha-fetoprotein (AFP) is a rare condition with only 11 cases reported in Japan to our knowledge. A 69-year-old man was admitted to our hospital for further examination of an incidental right renal tumor. Laboratory tests showed markedly increased serum level of AFP whereas both HBs antigen and anti-HCV antibody were negative. Computed tomography and magnetic resonance imaging imagings showed a right renal tumor but no tumor in liver, testis or lymph node. We performed right radical nephrectomy. Serum level of AFP declined within the normal range 7 weeks after nephrectomy according to its half-life curve. The tumor specimen was composed mainly of granular cells. Immunohistochemical examination of the tumor cells proved the presence of AFP in the cytoplasm. The possibility of AFP as a tumor marker of renal cell carcinoma in this case was presented |
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| Description: | Date Completed 04.10.2001 Date Revised 15.11.2006 published: Print Citation Status MEDLINE |
| ISSN: | 0018-1994 |