Integrating retroviral cassette extends gene delivery of HSV-1 expression vectors to dividing cells

Retroviral vectors have long been used in a wide variety of gene transfer applications but have certain drawbacks, such as small cargo size, limited tropism, and low titers. HSV expression vectors overcome these disadvantages, but, because they persist in target cells as nonreplicative episomes, the...

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Veröffentlicht in:BioTechniques. - 1993. - 31(2001), 2 vom: 15. Aug., Seite 394-402, 404-5
1. Verfasser: de Felipe, P (VerfasserIn)
Weitere Verfasser: Izquierdo, M, Wandosell, F, Lim, F
Format: Aufsatz
Sprache:English
Veröffentlicht: 2001
Zugriff auf das übergeordnete Werk:BioTechniques
Schlagworte:Journal Article Antibiotics, Antineoplastic Genetic Markers Viral Regulatory and Accessory Proteins SPP1 pac region protein, Bacteriophage SPP1 147015-70-1 Puromycin 4A6ZS6Q2CL