System for cleavable Fc fusion proteins using tobacco etch virus (TEV) protease

We describe a novel Fc fusion protein system that can be cleaved by tobacco etch virus (TEV) protease. This system is desirable because it takes advantage of the high specificity of TEV protease and its activity at 4 degrees C. We produced two TEV-Fc fusion proteins that contain the first three Ig d...

Ausführliche Beschreibung

Bibliographische Detailangaben
Veröffentlicht in:BioTechniques. - 1988. - 30(2001), 1 vom: 22. Jan., Seite 60-1, 64-6
1. Verfasser: Haspel, J (VerfasserIn)
Weitere Verfasser: Blanco, C, Jacob, J, Grumet, M
Format: Aufsatz
Sprache:English
Veröffentlicht: 2001
Zugriff auf das übergeordnete Werk:BioTechniques
Schlagworte:Research Support, Non-U.S. Gov't Technical Report DNA, Recombinant Immunoglobulin Fc Fragments Leukocyte L1 Antigen Complex Membrane Glycoproteins Neural Cell Adhesion Molecules Oligonucleotides Recombinant Fusion Proteins Endopeptidases mehr... EC 3.4.- TEV protease