Synergy in induction of increased renal allograft survival after portal vein infusion of dendritic cells transduced to express TGFbeta and IL-10, along with administration of CHO cells expressing the regulatory molecule OX-2

Synergy in induction of increased renal allograft survival after portal vein infusion of dendritic cells transduced to express TGFbeta and IL-10, along with administration of CHO cells expressing the regulatory molecule OX-2

Dendritic cells (DC), generated from C57BL/6 mouse bone marrow cells cultured with GM-CSF and IL-4 for 9 days, were engineered to express constitutively the cytokines TGFbeta, IL-10, and IL-12, using adenovirus vectors constructed using an E1-deleted replication-deficient recombinant adenovirus carr...

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Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 95(2000), 3 vom: 12. Juni, Seite 182-9
1. Verfasser: Gorczynski, R M (VerfasserIn)
Weitere Verfasser: Bransom, J, Cattral, M, Huang, X, Lei, J, Xiaorong, L, Min, W P, Wan, Y, Gauldie, J
Format: Aufsatz
Sprache:English
Veröffentlicht: 2000
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Adjuvants, Immunologic Antigens, CD Antigens, Surface Cytokines Transforming Growth Factor beta Interleukin-10 130068-27-8 antigens, CD200 UQ4V77A8VA