Efficient detection of thirty-seven new IL2RG mutations in human X-linked severe combined immunodeficiency

Efficient detection of thirty-seven new IL2RG mutations in human X-linked severe combined immunodeficiency

X-linked severe combined immunodeficiency (XSCID) is a rare and potentially fatal disease caused by mutations of IL2RG, the gene encoding the interleukin-2 receptor gamma chain, a component of multiple cytokine receptors that are essential for lymphocyte development and function. To date, over 100 d...

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Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 95(2000), 1 Pt 1 vom: 25. Apr., Seite 33-8
1. Verfasser: Niemela, J E (VerfasserIn)
Weitere Verfasser: Puck, J M, Fischer, R E, Fleisher, T A, Hsu, A P
Format: Aufsatz
Sprache:English
Veröffentlicht: 2000
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Receptors, Interleukin-2