Scanning by DOVAM-S detects all unique sequence changes in blinded analyses evidence that the scanning conditions are generic

Scanning by DOVAM-S detects all unique sequence changes in blinded analyses : evidence that the scanning conditions are generic

The [detection of virtually all mutations]-SSCP (DOVAM-S) is a highly sensitive variant of single strand conformation polymorphism (SSCP). Mutations in the factor IX gene were used to find a set of five SSCP conditions that detects virtually all mutations. A blinded analysis of the factor IX gene in...

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Bibliographische Detailangaben
Veröffentlicht in:BioTechniques. - 1991. - 28(2000), 4 vom: 19. Apr., Seite 746-50, 752-3
1. Verfasser: Buzin, C H (VerfasserIn)
Weitere Verfasser: Wen, C Y, Nguyen, V Q, Nozari, G, Mengos, A, Li, X, Chen, J S, Liu, Q, Gatti, R A, Fujimura, F K, Sommer, S S
Format: Aufsatz
Sprache:English
Veröffentlicht: 2000
Zugriff auf das übergeordnete Werk:BioTechniques
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Cell Cycle Proteins DNA-Binding Proteins Tumor Suppressor Proteins Factor VIII 9001-27-8 Factor IX 9001-28-9 ATM protein, human mehr... EC 2.7.11.1 Ataxia Telangiectasia Mutated Proteins Protein Serine-Threonine Kinases