Flutamide-induced hepatic disorder and serum concentrations of flutamide and its metabolites in patients with prostate cancer

Severe hepatotoxicity occurred in a prostate cancer patient treated with 375 mg of flutamide per day, 125 mg three times a day, for 11 weeks. Serial measurements of serum concentrations of flutamide and its metabolites in the patient showed an unusually high serum level and delayed elimination of fl...

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Veröffentlicht in:Hinyokika kiyo. Acta urologica Japonica. - 1962. - 45(1999), 12 vom: 20. Dez., Seite 821-6
1. Verfasser: Nakagawa, Y (VerfasserIn)
Weitere Verfasser: Koyama, M, Matsumoto, M
Format: Aufsatz
Sprache:Japanese
Veröffentlicht: 1999
Zugriff auf das übergeordnete Werk:Hinyokika kiyo. Acta urologica Japonica
Schlagworte:Case Reports Journal Article Androgen Antagonists Antineoplastic Agents, Hormonal Biomarkers Flutamide 76W6J0943E Aspartate Aminotransferases EC 2.6.1.1 Alanine Transaminase EC 2.6.1.2