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|a jpn
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|a Nakatsuji, H
|e verfasserin
|4 aut
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|a Concurrent platinum-based chemotherapy and radiotherapy for locally advanced bladder cancer
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|c 1999
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|a Text
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|a Date Completed 23.02.2000
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|a Date Revised 03.12.2021
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| 500 |
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|a published: Print
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|a Citation Status MEDLINE
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| 520 |
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|a Eight patients with locally advanced bladder cancer who were not candidates for radical cystectomy or concurrent intra-arterial chemotherapy and radiotherapy were treated with combined platinum-based chemotherapy and radiation therapy. Six of the eight patients (75%) achieved a clinical complete response (CR). The effect of therapy in four patients whose histopathological responses were evaluated was effect grade 3. One of the eight patients died of treatment-related myelosuppression. The other two patients died of intercurrent disease, while the remaining five patients are alive with preservation of a functional bladder. The 2-year overall survival rate was 87.5%. Adverse events due to chemotherapy were mainly bone marrow suppression. Those caused by radiation therapy were rectal irritability. We considered concurrent platinum-based chemotherapy and radiotherapy useful for the treatment of locally advanced bladder cancer
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|i Enthalten in
|t Hinyokika kiyo. Acta urologica Japonica
|d 1962
|g 45(1999), 11 vom: 23. Nov., Seite 745-8
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|x 0018-1994
|7 nnas
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