Treatment with tumor necrosis factor-alpha and granulocyte-macrophage colony-stimulating factor increases epidermal Langerhans' cell numbers in cancer patients

Treatment with tumor necrosis factor-alpha and granulocyte-macrophage colony-stimulating factor increases epidermal Langerhans' cell numbers in cancer patients

Dendritic cells (DCs) initiate primary and stimulate secondary T-cell responses. We conducted a phase I trial of tumor necrosis factor (TNF-alpha) and granulocyte-macrophage colony-stimulating factor (GM-CSF) in patients with cancer to increase DCs in peripheral blood or skin based on in vitro data...

Ausführliche Beschreibung

Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 93(1999), 3 vom: 15. Dez., Seite 209-21
1. Verfasser: Janik, J E (VerfasserIn)
Weitere Verfasser: Miller, L L, Kopp, W C, Taub, D D, Dawson, H, Stevens, D, Kostboth, P, Curti, B D, Conlon, K C, Dunn, B K, Donegan, S E, Ullrich, R, Alvord, W G, Gause, B L, Longo, D L
Format: Aufsatz
Sprache:English
Veröffentlicht: 1999
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Clinical Trial Clinical Trial, Phase I Journal Article Non-programmatic Carcinoembryonic Antigen Recombinant Proteins Tumor Necrosis Factor-alpha Granulocyte-Macrophage Colony-Stimulating Factor 83869-56-1