Decision support for clinical trial eligibility determination in breast cancer

We have developed a system for clinical trial eligibility determination where patients or primary care providers can enter clinical information about a patient and obtain a ranked list of clinical trials for which the patient is likely to be eligible. We used clinical trial eligibility information f...

Ausführliche Beschreibung

Bibliographische Detailangaben
Veröffentlicht in:Proceedings. AMIA Symposium. - 1998. - (1999) vom: 23., Seite 340-4
1. Verfasser: Ohno-Machado, L (VerfasserIn)
Weitere Verfasser: Wang, S J, Mar, P, Boxwala, A A
Format: Aufsatz
Sprache:English
Veröffentlicht: 1999
Zugriff auf das übergeordnete Werk:Proceedings. AMIA Symposium
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.
LEADER 01000naa a22002652 4500
001 NLM104963697
003 DE-627
005 20231222133638.0
007 tu
008 231222s1999 xx ||||| 00| ||eng c
028 5 2 |a pubmed24n0350.xml 
035 |a (DE-627)NLM104963697 
035 |a (NLM)10566377 
040 |a DE-627  |b ger  |c DE-627  |e rakwb 
041 |a eng 
100 1 |a Ohno-Machado, L  |e verfasserin  |4 aut 
245 1 0 |a Decision support for clinical trial eligibility determination in breast cancer 
264 1 |c 1999 
336 |a Text  |b txt  |2 rdacontent 
337 |a ohne Hilfsmittel zu benutzen  |b n  |2 rdamedia 
338 |a Band  |b nc  |2 rdacarrier 
500 |a Date Completed 01.02.2000 
500 |a Date Revised 13.11.2018 
500 |a published: Print 
500 |a Citation Status MEDLINE 
520 |a We have developed a system for clinical trial eligibility determination where patients or primary care providers can enter clinical information about a patient and obtain a ranked list of clinical trials for which the patient is likely to be eligible. We used clinical trial eligibility information from the National Cancer Institute's Physician Data Query (PDQ) database. We translated each free-text eligibility criterion into a machine executable statement using a derivation of the Arden Syntax. Clinical trial protocols were then structured as collections of these eligibility criteria using XML. The application compares the entered patient information against each of the eligibility criteria and returns a numerical score. Results are displayed in order of likelihood of match. We have tested our system using all phase II and III clinical trials for treatment of metastatic breast cancer found in the PDQ database. Preliminary results are encouraging 
650 4 |a Journal Article 
650 4 |a Research Support, Non-U.S. Gov't 
650 4 |a Research Support, U.S. Gov't, Non-P.H.S. 
650 4 |a Research Support, U.S. Gov't, P.H.S. 
700 1 |a Wang, S J  |e verfasserin  |4 aut 
700 1 |a Mar, P  |e verfasserin  |4 aut 
700 1 |a Boxwala, A A  |e verfasserin  |4 aut 
773 0 8 |i Enthalten in  |t Proceedings. AMIA Symposium  |d 1998  |g (1999) vom: 23., Seite 340-4  |w (DE-627)NLM098642928  |x 1531-605X  |7 nnns 
773 1 8 |g year:1999  |g day:23  |g pages:340-4 
912 |a GBV_USEFLAG_A 
912 |a SYSFLAG_A 
912 |a GBV_NLM 
912 |a GBV_ILN_350 
951 |a AR 
952 |j 1999  |b 23  |h 340-4