Expression of costimulatory molecules CD80 and/or CD86 by a Kaposi's sarcoma tumor cell line induces differential T-cell activation and proliferation
During physiological stimulation of resting T-cells, at least two activation signals by antigen presenting cells are required. Besides the first antigen-specific signal, the second costimulatory signal involves CD80 and CD86 expressed by the antigen presenting cell. These costimulatory molecules hav...
| Veröffentlicht in: | Clinical immunology (Orlando, Fla.). - 1999. - 91(1999), 3 vom: 01. Juni, Seite 345-53 |
|---|---|
| 1. Verfasser: | |
| Weitere Verfasser: | , , |
| Format: | Aufsatz |
| Sprache: | English |
| Veröffentlicht: |
1999
|
| Zugriff auf das übergeordnete Werk: | Clinical immunology (Orlando, Fla.) |
| Schlagworte: | Journal Article Research Support, U.S. Gov't, P.H.S. Antigens, CD B7-1 Antigen B7-2 Antigen CD86 protein, human Interleukin-2 Membrane Glycoproteins Interleukin-10 130068-27-8 mehr... |