IL-12-Independent costimulation pathways for interferon-gamma production in familial disseminated Mycobacterium avium complex infection

IL-12-Independent costimulation pathways for interferon-gamma production in familial disseminated Mycobacterium avium complex infection

We have described previously a family with an apparent genetic susceptibility to disseminated Mycobacterium avium complex infection and an underlying defect in IL-12 regulation leading to abnormally low interferon-gamma production. Their T cells appear to act normally when in the presence of normal...

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Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 91(1999), 2 vom: 09. Mai, Seite 234-41
1. Verfasser: Frucht, D M (VerfasserIn)
Weitere Verfasser: Sandberg, D I, Brown, M R, Gerstberger, S M, Holland, S M
Format: Aufsatz
Sprache:English
Veröffentlicht: 1999
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Antigens, CD B7-2 Antigen CD40 Antigens CD86 protein, human Membrane Glycoproteins CD40 Ligand 147205-72-9 Interleukin-12 187348-17-0 mehr... Interferon-gamma 82115-62-6