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01000naa a22002652 4500 |
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NLM101455712 |
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DE-627 |
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20231222122301.0 |
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231222s1999 xx ||||| 00| ||jpn c |
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|a pubmed24n0339.xml
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|a (DE-627)NLM101455712
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|a (NLM)10212792
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|a DE-627
|b ger
|c DE-627
|e rakwb
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|a jpn
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100 |
1 |
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|a Sumiyoshi, Y
|e verfasserin
|4 aut
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1 |
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|a Intra-arterial chemotherapy in combination with radiotherapy for invasive bladder cancer and prostate cancer
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|c 1999
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|a Text
|b txt
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|a ohne Hilfsmittel zu benutzen
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|a Band
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|2 rdacarrier
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|a Date Completed 27.04.1999
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|a Date Revised 20.11.2014
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|a published: Print
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|a Citation Status MEDLINE
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|a Forty-five patients with muscle-invasive bladder cancer treated with intra-arterial doxorubicin chemotherapy plus low-dose radiotherapy between September 1979 and March 1990 were retrospectively studied. Twenty-eight (62%) patients achieved a complete response (CR) and in all of them, a functional bladder could be preserved. The 10-year cause-specific survival rate of patients with CR was 95.5%, but that of patients not achieving a CR was 39%. These results demonstrate that in patients who achieve a CR with this treatment, we may be able to preserve a functional bladder. In a prospective study, we designed a new intra-arterial chemotherapy regimen in order to achieve a higher degree of effectiveness and to preserve a functional bladder. Twenty-three patients were treated with concurrent pirarubicin/cisplatin intra-arterial chemotherapy and radiotherapy after complete transurethral resection. Twenty-one (91%) patients achieved CR. One of these patients had relapse with lung metastases and was treated surgically. Two patients who did not achieve a CR died of cancer, and 21 patients are alive with preservation of functional bladder. For treatment of prostate cancer, we now administer only adjuvant intra-arterial chemotherapy plus irradiation for patients after radical prostatectomy
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|a Clinical Trial
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|a English Abstract
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4 |
|a Journal Article
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7 |
|a Doxorubicin
|2 NLM
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7 |
|a 80168379AG
|2 NLM
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|
7 |
|a pirarubicin
|2 NLM
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650 |
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7 |
|a D58G680W0G
|2 NLM
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650 |
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7 |
|a Cisplatin
|2 NLM
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650 |
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7 |
|a Q20Q21Q62J
|2 NLM
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700 |
1 |
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|a Hashine, K
|e verfasserin
|4 aut
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700 |
1 |
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|a Nakatsuji, H
|e verfasserin
|4 aut
|
773 |
0 |
8 |
|i Enthalten in
|t Hinyokika kiyo. Acta urologica Japonica
|d 1962
|g 45(1999), 2 vom: 15. Feb., Seite 155-8
|w (DE-627)NLM012631779
|x 0018-1994
|7 nnns
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|g volume:45
|g year:1999
|g number:2
|g day:15
|g month:02
|g pages:155-8
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|d 45
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