Mismatch cleavage detects base deletion in cystic fibrosis gene
The delta F508 is the most common defect in the cystic fibrosis (CF) gene; it involves in a 3-base deletion in codon 508 and results in the loss of a phenylalanine residue at amino acid position 508. Our previous results have shown the mismatch enzyme cleavage at the mismatch of a DNA duplex in iden...
| Veröffentlicht in: | BioTechniques. - 1993. - 25(1998), 4 vom: 15. Okt., Seite 692-6 |
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| Weitere Verfasser: | , , |
| Format: | Aufsatz |
| Sprache: | English |
| Veröffentlicht: |
1998
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| Zugriff auf das übergeordnete Werk: | BioTechniques |
| Schlagworte: | Journal Article Research Support, U.S. Gov't, Non-P.H.S. CFTR protein, human DNA Probes Cystic Fibrosis Transmembrane Conductance Regulator 126880-72-6 DNA Glycosylases EC 3.2.2.- N-Glycosyl Hydrolases mutY adenine glycosylase |