Competitive oligonucleotide single-base extension combined with mass spectrometric detection for mutation screening
A rapid, robust and widely applicable mutation detection scheme not requiring radioactivity or gel-based detection is introduced. It is a single-tube, competitive oligonucleotide single-base extension (COSBE) reaction using a pair of primers with the 3'-terminal base complementary to either the...
Veröffentlicht in: | BioTechniques. - 1993. - 23(1997), 4 vom: 15. Okt., Seite 710-4 |
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Weitere Verfasser: | , |
Format: | Aufsatz |
Sprache: | English |
Veröffentlicht: |
1997
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Zugriff auf das übergeordnete Werk: | BioTechniques |
Schlagworte: | Technical Report Journal Article CFTR protein, human DNA Primers Oligonucleotides Cystic Fibrosis Transmembrane Conductance Regulator 126880-72-6 |