Clinical investigation for recurrence and progression in Ta grades 1 and 2 bladder cancer
We treated 107 new patients with stage Ta, grades 1 and 2 transitional cell bladder carcinoma by transurethral resection during the past 23 years. The clinicopathological factors evaluated were grade, size, number and form of tumor. Fifty-five patients (51%) had recurrent tumors after initial resect...
Veröffentlicht in: | Hinyokika kiyo. Acta urologica Japonica. - 1962. - 43(1997), 3 vom: 06. März, Seite 185-9 |
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1. Verfasser: | |
Weitere Verfasser: | , , , , , , |
Format: | Aufsatz |
Sprache: | Japanese |
Veröffentlicht: |
1997
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Zugriff auf das übergeordnete Werk: | Hinyokika kiyo. Acta urologica Japonica |
Schlagworte: | English Abstract Journal Article |
Zusammenfassung: | We treated 107 new patients with stage Ta, grades 1 and 2 transitional cell bladder carcinoma by transurethral resection during the past 23 years. The clinicopathological factors evaluated were grade, size, number and form of tumor. Fifty-five patients (51%) had recurrent tumors after initial resection and progression (muscle invasion or metastasis) occurred in four patients (3.7%). The 5-year and 10-year recurrence free rates were 47.3 and 29.8%, respectively. Seven patients (6.5%) had grade 3 tumor (grade-up) at recurrence. An increase in T category to T1 (stage-up) occurred in 13 patients (12%), only one of whom later developed an invasive tumor (pT4). The size of tumor significantly affected the rate of recurrence (p < 0.01). Sessile tumor were at a significantly greater risk for progression (p < 0.05). Stage-up did not have a significant effect on progression, but grade-up was significantly risky for progression (p < 0.01). Initial grade 2 tumors were highly related to grade-up (p < 0.05) |
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Beschreibung: | Date Completed 13.06.1997 Date Revised 15.11.2006 published: Print Citation Status MEDLINE |
ISSN: | 0018-1994 |