Clinical investigation for recurrence and progression in Ta grades 1 and 2 bladder cancer

We treated 107 new patients with stage Ta, grades 1 and 2 transitional cell bladder carcinoma by transurethral resection during the past 23 years. The clinicopathological factors evaluated were grade, size, number and form of tumor. Fifty-five patients (51%) had recurrent tumors after initial resect...

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Bibliographische Detailangaben
Veröffentlicht in:Hinyokika kiyo. Acta urologica Japonica. - 1962. - 43(1997), 3 vom: 06. März, Seite 185-9
1. Verfasser: Takei, K (VerfasserIn)
Weitere Verfasser: Kotake, T, Masai, M, Ito, H, Nagao, K, Chiba, K, Saito, K, Hirokawa, M
Format: Aufsatz
Sprache:Japanese
Veröffentlicht: 1997
Zugriff auf das übergeordnete Werk:Hinyokika kiyo. Acta urologica Japonica
Schlagworte:English Abstract Journal Article
Beschreibung
Zusammenfassung:We treated 107 new patients with stage Ta, grades 1 and 2 transitional cell bladder carcinoma by transurethral resection during the past 23 years. The clinicopathological factors evaluated were grade, size, number and form of tumor. Fifty-five patients (51%) had recurrent tumors after initial resection and progression (muscle invasion or metastasis) occurred in four patients (3.7%). The 5-year and 10-year recurrence free rates were 47.3 and 29.8%, respectively. Seven patients (6.5%) had grade 3 tumor (grade-up) at recurrence. An increase in T category to T1 (stage-up) occurred in 13 patients (12%), only one of whom later developed an invasive tumor (pT4). The size of tumor significantly affected the rate of recurrence (p < 0.01). Sessile tumor were at a significantly greater risk for progression (p < 0.05). Stage-up did not have a significant effect on progression, but grade-up was significantly risky for progression (p < 0.01). Initial grade 2 tumors were highly related to grade-up (p < 0.05)
Beschreibung:Date Completed 13.06.1997
Date Revised 15.11.2006
published: Print
Citation Status MEDLINE
ISSN:0018-1994