Comparative histological analysis of needle biopsy specimens, prostatectomized specimens and metastatic lymph nodes in prostatic adenocarcinoma--on the basis of the WHO histological classification

The histological characteristics were comparatively analyzed among biopsy specimens, surgically removed prostates and metastatic lymph nodes obtained from 60 patients with prostatic adenocarcinoma treated by radical prostatectomy. According to the WHO-Mostifi's classification, the proportion of...

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Veröffentlicht in:Hinyokika kiyo. Acta urologica Japonica. - 1962. - 43(1997), 2 vom: 18. Feb., Seite 97-101
1. Verfasser: Kondo, I (VerfasserIn)
Weitere Verfasser: Miura, T, Fujinami, K, Satomi, Y, Ida, T, Ishizuka, E, Uemura, H, Noguchi, S, Kubota, Y, Hosaka, M, Harada, M
Format: Aufsatz
Sprache:Japanese
Veröffentlicht: 1997
Zugriff auf das übergeordnete Werk:Hinyokika kiyo. Acta urologica Japonica
Schlagworte:Comparative Study English Abstract Journal Article
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245 1 0 |a Comparative histological analysis of needle biopsy specimens, prostatectomized specimens and metastatic lymph nodes in prostatic adenocarcinoma--on the basis of the WHO histological classification 
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520 |a The histological characteristics were comparatively analyzed among biopsy specimens, surgically removed prostates and metastatic lymph nodes obtained from 60 patients with prostatic adenocarcinoma treated by radical prostatectomy. According to the WHO-Mostifi's classification, the proportion of the 6 histologic components, large and/or small simple glands (LSG), micro-glands (MIC), cribriorm (CRB), fused glands (FUS), medullary/solid (MED) and columns-cords/trabecular (C-C), was determined semiquantitatively. LSG, MIC, and CRB are androgen-sensitive components, while FUS, MED and C-C are androgen-refractory components. The proportions of 5 histologic components excluding MIC were similar in the biopsy and prostate specimens. In 78.3% of the patients, the presence (or absence) of androgen-refactory components in the biopsy specimens coincided with that in the prostate specimens. However, the histologic except for the C-C component. Metastatic lymph nodes contained androgen-refactory components in all cases and tended to have more CRB and FUS and fewer LSG. The histology of the needle biopsy specimens may reflect that of the prostate glands, and may serve as a valuable parameter for determining therapeutic modalities. In addition, androgen-refactory components are frequently present in lymph node metastasis 
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650 4 |a English Abstract 
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700 1 |a Miura, T  |e verfasserin  |4 aut 
700 1 |a Fujinami, K  |e verfasserin  |4 aut 
700 1 |a Satomi, Y  |e verfasserin  |4 aut 
700 1 |a Ida, T  |e verfasserin  |4 aut 
700 1 |a Ishizuka, E  |e verfasserin  |4 aut 
700 1 |a Uemura, H  |e verfasserin  |4 aut 
700 1 |a Noguchi, S  |e verfasserin  |4 aut 
700 1 |a Kubota, Y  |e verfasserin  |4 aut 
700 1 |a Hosaka, M  |e verfasserin  |4 aut 
700 1 |a Harada, M  |e verfasserin  |4 aut 
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