Design and preparation of a multimeric self-cleaving hammerhead ribozyme
The activity of a ribozyme can be impaired by additional sequences at the 5' and 3' termini of the catalytic sequence. To approach this problem, a system was designed that minimizes sequences upstream and downstream from active regions of a hammerhead ribozyme and allows delivery of a larg...
| Veröffentlicht in: | BioTechniques. - 1993. - 22(1997), 2 vom: 31. Feb., Seite 338-45 |
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| 1. Verfasser: | |
| Weitere Verfasser: | , , |
| Format: | Aufsatz |
| Sprache: | English |
| Veröffentlicht: |
1997
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| Zugriff auf das übergeordnete Werk: | BioTechniques |
| Schlagworte: | Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. Macromolecular Substances RNA, Catalytic RNA, Messenger RNA, Viral |